Valsartan
Everything that changed this substance, across every flow that resolves to it. Back to the substance
fo-11d8b2a69f185281
Changes
60| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 9,551 | bootstrap_labels | prefLabel | — | [{"@value":"(2s)-3-methyl-2-(n-{[2'-(1h-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid","@… | Bootstrapped prefLabel from legacy name field |
| 9,552 | bootstrap_labels | name | (2s)-3-methyl-2-(n-{[2'-(1h-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid | — | Purged legacy name field to enforce prefLabel usage |
| 9,553 | bootstrap_labels | synonyms | ["l-valine,n-(1-oxopentyl)-n-[[2'","-(2h-tetrazol-5-yl)[1,1'","-biphenyl]-4-yl]methyl]-othernamesl-valine,n-(1-… | [] | Removed legacy synonyms field in favor of structured labels |
| 42,146 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 42,147 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 45,800 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Ground level","population_density":"Urban (>1000 people/square mil… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 45,801 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-grle-ur10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 49,954 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Non-agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 49,955 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-noag | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 58,226 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Ocean"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 58,227 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-ocea | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 58,518 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 58,519 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 67,100 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 67,101 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 142,874 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 142,875 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-agri | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 156,516 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","indoor":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 156,517 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-indr-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 171,168 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 171,169 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 181,194 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 181,195 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 184,212 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Medium stack, <150 meters","population_density":"Rural (<1000 peop… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 184,213 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-mest15me-ru10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 186,736 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 186,737 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 191,816 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 191,817 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 216,520 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 223,344 | normalize_name_case | prefLabel | [{"@value":"(2s)-3-methyl-2-(n-{[2'-(1h-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic acid","@… | [{"@value":"(2s)-3-methyl-2-(n-{[2'-(1h-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic Acid","@… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 236,317 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C24H29N5O3… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 236,318 | enrich_references | skos_definition | — | [{"@value":"A monocarboxylic acid amide consisting of L-valine in which the amino hydrogens have been replaced by a pen… | Merged ChEBI/PubChem definitions into skos:definition |
| 236,319 | enrich_references | references | [] | [{"@id":"drugcentral:2806","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":"… | Added references with provenance; cas_numbers=['137862-53-4']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_9927']; candidate_pubchem_cids=[5650, 8063, 60846, 164050, 5284633]; selected_pubchem_cids=[60846]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 250,946 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C24H29N5O3… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C24H29N5O3… | rdkit_pre_consensus from 'CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)O'; added: inchi2d_string |
| 255,757 | chebi_altlabels | altLabel | [] | [{"@value":"(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine","@language":"en","source":{"prov:wasG… | Added 6 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 257,676 | consensus_match | prefLabel | [{"@value":"(2s)-3-methyl-2-(n-{[2'-(1h-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoic Acid","@… | [{"@value":"Valsartan","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttributedTo":"conse… | cas=137862-53-4; cc_chebi_agreed_name='Valsartan'; object_uuid=fo-11d8b2a69f185281 |
| 257,677 | consensus_match | altLabel | [{"@value":"(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine","@language":"en","source":{"prov:wasG… | [{"@value":"(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine","@language":"en","source":{"prov:wasG… | cas=137862-53-4; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-11d8b2a69f185281 |
| 257,678 | consensus_match | altLabel | [{"@value":"(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine","@language":"en","source":{"prov:wasG… | [{"@value":"(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine","@language":"en","source":{"prov:wasG… | group_key=(2s)-3-methyl-2-(n-{[2'-(1h-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoicacid||dimension=Environmental > media=Air > strata=Aircraft cruise height; cas=137862-53-4; added Common Chemistry CAS names as altLabel: (2<em>S</em>)-3-Methyl-2-[pentanoyl-[[4-[2-(2<em>H</em>-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid, <em>N</em>-(1-Oxopentyl)-<em>N</em>-[[2′-(2<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-<span class="text-smallcaps">L</span>-valine, <span class="text-smallcaps">L</span>-Valine, <em>N</em>-(1-oxopentyl)-<em>N</em>-[[2′-(1<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, <span class="text-smallcaps">L</span>-Valine, <em>N</em>-(1-oxopentyl)-<em>N</em>-[[2′-(2<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, CGP 48933, Cardopan, Nisis, Tareg, Valsacor, Valsarect, Valsartanin, Valtensin, Vazar; object_uuid=fo-11d8b2a69f185281 |
| 257,679 | consensus_match | cas_match_labels | — | {"137862-53-4":"exactMatch"} | group_key=(2s)-3-methyl-2-(n-{[2'-(1h-1,2,3,4-tetrazol-5-yl)-[1,1-biphenyl]-4-yl]methyl}pentanamido)butanoicacid||dimension=Environmental > media=Air > strata=Aircraft cruise height; group_sources=['chebi']; cas_sources={'137862-53-4': ['chebi']}; assigned CAS labels from group consensus; object_uuid=fo-11d8b2a69f185281: {'137862-53-4': 'exactMatch'} |
| 276,148 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C24H29N5O3… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C24H29N5O3… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine' |
| 282,723 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C24H29N5O3… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C24H29N5O3… | rdkit_post_consensus from 'CCCCC(=O)N(Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)[C@H](C(=O)O)C(C)C'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 289,275 | strip_catalogue_altlabels | altLabel | [{"@value":"(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine","@language":"en","source":{"prov:wasG… | [{"@value":"(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine","@language":"en","source":{"prov:wasG… | Removed 1 catalogue altLabel value(s): 'CGP 48933' (grade code) |
| 302,118 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/096a6ee3-a03a-… | associations resolved on the elementary layer |
| 303,946 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/0e46cc40-7f86-… | associations resolved on the elementary layer |
| 306,024 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/154d4283-91b3-… | associations resolved on the elementary layer |
| 310,155 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/20137805-2cc1-… | associations resolved on the elementary layer |
| 310,301 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/209df81c-c027-… | associations resolved on the elementary layer |
| 314,587 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/2d9776ab-3704-… | associations resolved on the elementary layer |
| 352,459 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/9c73f584-2079-… | associations resolved on the elementary layer |