Betamethasone
Everything that changed this substance, across every flow that resolves to it. Back to the substance
fo-173c4385260d38e2
Changes
58| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 18,435 | bootstrap_labels | prefLabel | — | [{"@value":"9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-meth… | Bootstrapped prefLabel from legacy name field |
| 18,436 | bootstrap_labels | name | 9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-methylpregna-1,4… | — | Purged legacy name field to enforce prefLabel usage |
| 18,437 | bootstrap_labels | synonyms | ["betamethasone","(1r,2s,10s,11s,13s,14r,15s,17s)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetrac… | [] | Removed legacy synonyms field in favor of structured labels |
| 59,291 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 59,292 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 69,987 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","indoor":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 69,988 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-indr-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 71,203 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Medium stack, <150 meters","population_density":"Rural (<1000 peop… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 71,204 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-mest15me-ru10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 78,863 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 78,864 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 106,905 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 106,906 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 109,429 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Ground level","population_density":"Urban (>1000 people/square mil… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 109,430 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-grle-ur10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 110,327 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Non-agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 110,328 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-noag | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 127,937 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 127,938 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 140,399 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Ocean"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 140,400 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-ocea | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 141,719 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 141,720 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 151,431 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 151,432 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-agri | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 165,961 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 165,962 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 191,629 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 191,630 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 219,368 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 244,405 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 244,406 | enrich_references | skos_definition | — | [] | Merged ChEBI/PubChem definitions into skos:definition |
| 244,407 | enrich_references | references | [] | [{"@id":"beilstein:3176546","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":… | Added references with provenance; cas_numbers=['378-44-9']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_3077']; candidate_pubchem_cids=[3003, 9782, 91620, 146364, 969487, 5702012, 6546942, 6710614, 11014684, 12358601, 13075978, 21140858, 40469538, 71299643, 121231050, 123133873, 133634290, 145705940, 163198893, 163285078, 171035078, 176541415]; selected_pubchem_cids=[9782]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 253,287 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | rdkit_pre_consensus from 'CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C'; added: inchi2d_string, monoisotopic_mass |
| 256,806 | chebi_altlabels | altLabel | [] | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | Added 10 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 263,376 | consensus_match | prefLabel | [{"@value":"9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-meth… | [{"@value":"Betamethasone","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttributedTo":"b… | cas=378-44-9; cc_chebi_agreed_name='Betamethasone'; object_uuid=fo-173c4385260d38e2 |
| 263,377 | consensus_match | altLabel | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | cas=378-44-9; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-173c4385260d38e2 |
| 263,378 | consensus_match | altLabel | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | group_key=9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-methylpregna-1,4-diene-3,20-dione||dimension=Environmental > media=Water > water_body=Surface water; cas=378-44-9; added Common Chemistry CAS names as altLabel: (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9-Fluoro-16β-methylprednisolone, 9α-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 9α-Fluoro-16β-methylprednisolone, Becort, Bedifos, Betacorlan, Betacortil, Betacortril, Betametasone, Betamethazone, Betapredol, Betasolon, Bethamethasone, Betnelan, Betsolan, Bifas, Celestan, Celestene, Celeston, Celestone, Cidoten, Colircusi betamida, Dermabet, Desacort-Beta, Ethamethasoneb, Flosteron, Flubenisolone, MeSH ID: D001623, NSC 39470, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11β,16β)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, Rinderon A, Sch 4831, Visubeta, β-Methasone, β-Methasone alcohol; object_uuid=fo-173c4385260d38e2 |
| 263,379 | consensus_match | cas_match_labels | — | {"378-44-9":"exactMatch"} | group_key=9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-methylpregna-1,4-diene-3,20-dione||dimension=Environmental > media=Water > water_body=Surface water; group_sources=['chebi', 'ec_inventory']; cas_sources={'378-44-9': ['chebi', 'ec_inventory']}; assigned CAS labels from group consensus; object_uuid=fo-173c4385260d38e2: {'378-44-9': 'exactMatch'} |
| 278,498 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione' |
| 285,264 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | rdkit_post_consensus from 'C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 290,977 | strip_catalogue_altlabels | altLabel | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | Removed 2 catalogue altLabel value(s): 'NSC 39470' (registry code), 'Sch 4831' (grade code) |
| 310,705 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/21f25474-c65f-… | associations resolved on the elementary layer |
| 316,051 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/32800a48-a79e-… | associations resolved on the elementary layer |
| 316,659 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/335379ec-1ab7-… | associations resolved on the elementary layer |
| 320,485 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/3ecd932d-bbfa-… | associations resolved on the elementary layer |
| 334,488 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/6026432c-a4e6-… | associations resolved on the elementary layer |
| 335,751 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/649759d8-7c96-… | associations resolved on the elementary layer |
| 336,200 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/65a87e13-ca59-… | associations resolved on the elementary layer |
| 345,007 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/83774bb6-bedc-… | associations resolved on the elementary layer |