Melphalan
Everything that changed this substance, across every flow that resolves to it. Back to the substance
fo-2379f5b4f316c79b
Changes
60| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 3,479 | bootstrap_labels | prefLabel | — | [{"@value":"phenylalanine mustard","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttribu… | Bootstrapped prefLabel from legacy name field |
| 3,480 | bootstrap_labels | name | phenylalanine mustard | — | Purged legacy name field to enforce prefLabel usage |
| 3,481 | bootstrap_labels | synonyms | ["(+)-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine","(+)-3-[p-[Bis(2-chloroethyl)amino]phenyl]alanine","(p-Di(2-chloroe… | [] | Removed legacy synonyms field in favor of structured labels |
| 12,779 | bootstrap_labels | synonyms | ["melphalan","(2s)-2-amino-3-{4-[bis(2-chloroethyl)amino]phenyl}propanoicacid","4-[bis(2-chloroethyl)amino]-d-phenylala… | [] | Removed legacy synonyms field in favor of structured labels |
| 28,658 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 28,659 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 46,818 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","indoor":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 46,819 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-indr-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 203,316 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 203,317 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-agri | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 203,318 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 203,319 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 203,320 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 203,321 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 203,322 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 203,323 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 203,324 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Ground level","population_density":"Urban (>1000 people/square mil… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 203,325 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-grle-ur10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 203,326 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Medium stack, <150 meters","population_density":"Rural (<1000 peop… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 203,327 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-mest15me-ru10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 203,328 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 203,329 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 203,330 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 203,331 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 203,332 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 203,333 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 203,334 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Non-agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 203,335 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-noag | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 203,336 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Ocean"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 203,337 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-ocea | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 214,500 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 221,896 | normalize_name_case | prefLabel | [{"@value":"phenylalanine mustard","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttribu… | [{"@value":"Phenylalanine Mustard","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttribu… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 230,534 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 230,535 | enrich_references | skos_definition | — | [{"@value":"A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-positi… | Merged ChEBI/PubChem definitions into skos:definition |
| 230,536 | enrich_references | references | [] | [{"@id":"drugcentral:1678","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":"… | Added references with provenance; cas_numbers=['148-82-3']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_28876']; candidate_pubchem_cids=[4053, 460612, 9927978, 66780577]; selected_pubchem_cids=[460612]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 249,289 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | rdkit_pre_consensus from 'C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl'; added: inchi2d_string, monoisotopic_mass |
| 254,804 | chebi_altlabels | altLabel | [] | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | Added 17 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 270,639 | consensus_match | prefLabel | [{"@value":"Phenylalanine Mustard","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttribu… | [{"@value":"Melphalan","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttributedTo":"conse… | cas=148-82-3; cc_chebi_agreed_name='Melphalan'; object_uuid=fo-2379f5b4f316c79b |
| 270,640 | consensus_match | altLabel | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | cas=148-82-3; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-2379f5b4f316c79b |
| 270,641 | consensus_match | altLabel | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | group_key=phenylalaninemustard||dimension=Environmental > media=Air > strata=Aircraft cruise height; cas=148-82-3; added Common Chemistry CAS names as altLabel: 3025CB, 67: PN: WO2010011890 PAGE: 37 claimed protein, <span class="text-smallcaps">L</span>-Phenylalanine mustard hydrochloride, <span class="text-smallcaps">L</span>-Phenylalanine, 4-[bis(2-chloroethyl)amino]-, <span class="text-smallcaps">L</span>-Sarcolysin, <span class="text-smallcaps">L</span>-Sarkolysin, Alanine nitrogen mustard, Alanine, 3-[<em>p</em>-[bis(2-chloroethyl)amino]phenyl]-, <span class="text-smallcaps">L</span>-, Alkeran, CB 3025, Levofalan, Levofolan, Levopholan, MeSH ID: D008558, Melfalan, NSC 241286, NSC 8806, Sarcoclorin; object_uuid=fo-2379f5b4f316c79b |
| 270,642 | consensus_match | cas_match_labels | — | {"148-82-3":"exactMatch"} | group_key=phenylalaninemustard||dimension=Environmental > media=Air > strata=Aircraft cruise height; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'148-82-3': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-2379f5b4f316c79b: {'148-82-3': 'exactMatch'} |
| 274,411 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine' |
| 280,847 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | rdkit_post_consensus from 'N[C@@H](Cc1ccc(N(CCCl)CCCl)cc1)C(=O)O'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 287,963 | strip_catalogue_altlabels | altLabel | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | Removed 3 catalogue altLabel value(s): 'CB 3025' (grade code), 'NSC 241286' (registry code), 'NSC 8806' (registry code) |
| 295,373 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/041fd22d-6556-… | associations resolved on the elementary layer |
| 304,436 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/100a8b0e-cacf-… | associations resolved on the elementary layer |
| 382,692 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/fe0acd60-3ddc-… | associations resolved on the elementary layer |
| 382,693 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/fe0acd60-3ddc-… | associations resolved on the elementary layer |
| 382,694 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/fe0acd60-3ddc-… | associations resolved on the elementary layer |
| 382,695 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/fe0acd60-3ddc-… | associations resolved on the elementary layer |