Pyrimethamine
Everything that changed this substance, across every flow that resolves to it. Back to the substance
fo-2dc33340e0314b3e
Changes
57| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 9,639 | bootstrap_labels | prefLabel | — | [{"@value":"pyrimethamine","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"… | Bootstrapped prefLabel from legacy name field |
| 9,640 | bootstrap_labels | name | pyrimethamine | — | Purged legacy name field to enforce prefLabel usage |
| 9,641 | bootstrap_labels | synonyms | ["2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine","2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine","2,4-Diamino-5-c… | [] | Removed legacy synonyms field in favor of structured labels |
| 24,623 | bootstrap_labels | synonyms | ["pyrimethamine","5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine","5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine",… | [] | Removed legacy synonyms field in favor of structured labels |
| 42,238 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 42,239 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 44,244 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 44,245 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 46,648 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 46,649 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 47,302 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Non-agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 47,303 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-noag | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 50,368 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 50,369 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-agri | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 55,036 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 55,037 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 67,126 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 67,127 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 70,148 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Medium stack, <150 meters","population_density":"Rural (<1000 peop… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 70,149 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-mest15me-ru10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 113,052 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 113,053 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 120,698 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Ocean"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 120,699 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-ocea | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 146,552 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 146,553 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 154,446 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Ground level","population_density":"Urban (>1000 people/square mil… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 154,447 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-grle-ur10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 163,386 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","indoor":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 163,387 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-indr-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 216,542 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 223,353 | normalize_name_case | prefLabel | [{"@value":"pyrimethamine","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"… | [{"@value":"Pyrimethamine","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 236,392 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H13ClN4… | Added ChEBI/PubChem properties (chebi_ids=2, pubchem_cids=1) |
| 236,393 | enrich_references | skos_definition | — | [{"@value":"An aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl gr… | Merged ChEBI/PubChem definitions into skos:definition |
| 236,394 | enrich_references | references | [] | [{"@id":"drugcentral:2332","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":"… | Added references with provenance; cas_numbers=['58-14-0']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_47343', 'http://purl.obolibrary.org/obo/CHEBI_8673']; candidate_pubchem_cids=[4993, 44201349]; selected_pubchem_cids=[4993]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 250,963 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H13ClN4… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H13ClN4… | rdkit_pre_consensus from 'CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl'; added: monoisotopic_mass |
| 255,763 | chebi_altlabels | altLabel | [] | [{"@value":"2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | Added 22 ChEBI synonym(s) as altLabel from 2 linked ChEBI record(s) |
| 271,225 | consensus_match | altLabel | [{"@value":"2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | [{"@value":"2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | group_key=pyrimethamine||dimension=Environmental > media=Water > water_body=Unknown; cas=58-14-0; added Common Chemistry CAS names as altLabel: 2,4-Diamino-5-<em>p</em>-chlorophenyl-6-ethylpyrimidine, 2,4-Pyrimidinediamine, 5-(4-chlorophenyl)-6-ethyl-, 4753 R.P., 5-(4-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine, 5-(<em>P</em>-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine, BW 50-63, Broad ID:BRD-K 88429204, Darachlor, Darapram, Daraprim, Daraprime, Erbaprelina, Khloridin, Malacid, Malocid, Malocide, MeSH ID: D011739, NSC 3061, Pyrimidine, 2,4-diamino-5-(<em>p</em>-chlorophenyl)-6-ethyl-, RP 4753, Tindurin, Tinduring, WR 2978; object_uuid=fo-2dc33340e0314b3e |
| 271,226 | consensus_match | cas_match_labels | — | {"58-14-0":"exactMatch"} | group_key=pyrimethamine||dimension=Environmental > media=Water > water_body=Unknown; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'58-14-0': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-2dc33340e0314b3e: {'58-14-0': 'exactMatch'} |
| 276,150 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H13ClN4… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H13ClN4… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine' |
| 282,730 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H13ClN4… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H13ClN4… | rdkit_post_consensus from 'CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 289,277 | strip_catalogue_altlabels | altLabel | [{"@value":"2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | [{"@value":"2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_a… | Removed 3 catalogue altLabel value(s): 'NSC 3061' (registry code), 'RP 4753' (grade code), 'WR 2978' (grade code) |
| 302,144 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/098d6f25-2874-… | associations resolved on the elementary layer |
| 303,148 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/0d3711fb-9222-… | associations resolved on the elementary layer |
| 304,351 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/0fbd2c76-08f3-… | associations resolved on the elementary layer |
| 304,678 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/10d3f099-6fb3-… | associations resolved on the elementary layer |
| 306,211 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/16147026-cc41-… | associations resolved on the elementary layer |
| 308,545 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/1c40d1fb-3346-… | associations resolved on the elementary layer |
| 314,580 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/2da3dcfe-7030-… | associations resolved on the elementary layer |
| 316,091 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/32bc2a1c-f666-… | associations resolved on the elementary layer |