Ibuprofen
Everything that changed this substance, across every flow that resolves to it. Back to the substance
fo-6d363d0bdaf194d3
Changes
57| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 1,415 | bootstrap_labels | prefLabel | — | [{"@value":"ibuprofen","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"brig… | Bootstrapped prefLabel from legacy name field |
| 1,416 | bootstrap_labels | name | ibuprofen | — | Purged legacy name field to enforce prefLabel usage |
| 1,417 | bootstrap_labels | synonyms | ["ibuprofen","2-(4-isobutyl-phenyl)-propionic acid","benzeneacetic acid, ?-methyl-4-(2-methylpropyl)-","2-[4-(2-methylp… | [] | Removed legacy synonyms field in favor of structured labels |
| 3,873 | bootstrap_labels | synonyms | ["( inverted question mark)-Ibuprofen","(+-)-2-(p-Isobutylphenyl)propionic acid","(+-)-Ibuprofen","(+-)-Ibuprophen","(+… | [] | Removed legacy synonyms field in favor of structured labels |
| 26,881 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 26,882 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 29,369 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Medium stack, <150 meters","population_density":"Rural (<1000 peop… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 29,370 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-mest15me-ru10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 47,645 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 47,646 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 62,413 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Ocean"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 62,414 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-ocea | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 71,471 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 71,472 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 75,515 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Ground level","population_density":"Urban (>1000 people/square mil… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 75,516 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-grle-ur10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 75,745 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 75,746 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 110,921 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 110,922 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 116,733 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 116,734 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-agri | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 133,603 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 133,604 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 164,657 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","indoor":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 164,658 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-indr-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 179,809 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 179,810 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 186,445 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Non-agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 186,446 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-noag | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 213,810 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 221,417 | normalize_name_case | prefLabel | [{"@value":"ibuprofen","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"brig… | [{"@value":"Ibuprofen","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"brig… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 228,542 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18O2"]… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 228,543 | enrich_references | skos_definition | — | [{"@value":"A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by… | Merged ChEBI/PubChem definitions into skos:definition |
| 228,544 | enrich_references | references | [] | [{"@id":"drugcentral:1407","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":"… | Added references with provenance; cas_numbers=['15687-27-1']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_5855']; candidate_pubchem_cids=[3672, 114864, 5338317, 6926382, 77134427]; selected_pubchem_cids=[3672]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 254,549 | chebi_altlabels | altLabel | [] | [{"@value":"(+-)-2-(p-isobutylphenyl)propionic acid","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels"… | Added 54 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 267,912 | consensus_match | altLabel | [{"@value":"(+-)-2-(p-isobutylphenyl)propionic acid","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels"… | [{"@value":"(+-)-2-(p-isobutylphenyl)propionic acid","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels"… | group_key=ibuprofen||dimension=Environmental > media=Air > strata=Aircraft cruise height; cas=15687-27-1; added Common Chemistry CAS names as altLabel: (4-Isobutylphenyl)-α-methylacetic acid, (±)-2-(<em>p</em>-Isobutylphenyl)propionic acid, (±)-Ibuprofen, (±)-Ibuprophen, (±)-α-Methyl-4-(2-methylpropyl)benzeneacetic acid, 2-(4′-Isobutylphenyl)propionic acid, 2-(<em>p</em>-Isobutylphenyl)propionic acid, 4-Isobutyl-α-methylphenylacetic acid, <em>dl</em>-Ibuprofen, <em>p</em>-Isobutyl-2-phenylpropionic acid, <em>p</em>-Isobutylhydratropic acid, Act 3, Actiprofen, Actron Ibuprofen, Adex 200, Alaxan, Algi-Flanderil, Algiflex, Algofen, Am-Fam 400, Anafen, Andran, Antarene, Antiflam, Apo-Ibuprofen, Artofen, Artril, Artril 300, Atril 300, BC 1054, Balkaprofen, Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, Betaprofen, Bloom, Bonifen, Boosten, Brofen, Brufanic, Brufen 400, Brufen Retard, Bruflam, Brustan-N, Buluofen, Buprol, Burana, Butacortelone, Caldolor, Carol, Cetafen Plus, Cobo, Codral Period Pain, Dansida, Deep relief, Dentigoa, Dibufen, Diverin, Dolmaral, Dolocyl, Dolofen, Dolofen F, Dolomax, Donjust B, Doretrim, Dorival, Drin, Easifon, Emflam, Emflam 200, Espen, Fenbid, Fenspan, Flarin, Focus, Genafen, Gofen, Gynofug, Hydratropic acid, <em>p</em>-isobutyl-, IB 100, IP 82, Ibosure, Ibren, Ibu-Tab, Ibu-slow, IbuHexal, Ibubel, Ibuberofen, Ibudex, Ibufen, Ibuflam, Ibuflamar, Ibuflamol, Ibufug, Ibugen, Ibugesic, Ibuleve, Ibulgan, Ibupirac, Ibupril, Ibuprofen Belupo, Ibuprohm, Ibusal, Ibutad, Ifen, Inflam, Inza, Ipren, Iprogel, Irfen, Isodol, Juilifen, Librofem, Lidifen, Lopane, MeSH ID: D007052, Medprofen, Mensoton, Moment, MomentAct, Motrin IB, Multifen, NSC 256857, Nagifen-D, Napacetin, Nobafon, Nobfelon, Noritis, Norton, Novogent, Novoprofen, Nureflex, Omafen, Optifen, Opturem, Ostarin, Ostofen, Paduden, Panafen, Pantrop, Paucofen, Paxofen, Pedea, Pedifen, Perofen, Proartinal, Profen, Proflex, Prontalgin, Proris, Provil, Provon, Quadrax, RD 13621, Rafen, Ranofen, Recidol, Relcofen, Rufin, Rupan, Spedifen Zambon, Stelar, Stelar (pharmaceutical), Syntofene, Tabalon 400, Tarein, Tatanal, Tofen, U 18753, Unipron, Upfen, Uprofen, Zafen, Zofen, α-(4-Isobutylphenyl)propionic acid, α-Methyl-4-(2-methylpropyl)benzeneacetic acid; object_uuid=fo-6d363d0bdaf194d3 |
| 267,913 | consensus_match | cas_match_labels | — | {"15687-27-1":"exactMatch"} | group_key=ibuprofen||dimension=Environmental > media=Air > strata=Aircraft cruise height; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'15687-27-1': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-6d363d0bdaf194d3: {'15687-27-1': 'exactMatch'} |
| 273,839 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18O2"]… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18O2"]… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from 'Ibuprofen' |
| 280,226 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18O2"]… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18O2"]… | rdkit_post_consensus from 'CC(C)Cc1ccc(C(C)C(=O)O)cc1'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 287,555 | strip_catalogue_altlabels | altLabel | [{"@value":"(+-)-2-(p-isobutylphenyl)propionic acid","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels"… | [{"@value":"(+-)-2-(p-isobutylphenyl)propionic acid","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels"… | Removed 13 catalogue altLabel value(s): 'Act 3' (grade code), 'Adex 200' (grade code), 'Artril 300' (trade name), 'Atril 300' (trade name), 'BC 1054' (grade code), 'Brufen 400' (trade name), 'Emflam 200' (trade name), 'IB 100' (grade code), 'IP 82' (grade code), 'NSC 256857' (registry code), 'RD 13621' (grade code), 'Tabalon 400' (trade name), 'U 18753' (grade code) |
| 294,525 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/01b19d4e-cb7d-… | associations resolved on the elementary layer |
| 295,764 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/0457059b-425e-… | associations resolved on the elementary layer |
| 304,891 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/1178baf5-ac16-… | associations resolved on the elementary layer |
| 312,265 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/27417319-9630-… | associations resolved on the elementary layer |
| 316,793 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/33d3f63c-5290-… | associations resolved on the elementary layer |
| 318,812 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/3ac09ded-54c4-… | associations resolved on the elementary layer |
| 318,927 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/3b216ec9-2892-… | associations resolved on the elementary layer |
| 336,497 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/66a76baf-61f0-… | associations resolved on the elementary layer |
| 339,402 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/7072c641-bc24-… | associations resolved on the elementary layer |