Losartan
Everything that changed this substance, across every flow that resolves to it. Back to the substance
fo-71d33d9cf32dbbc6
Changes
57| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 20,683 | bootstrap_labels | prefLabel | — | [{"@value":"[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol","@lan… | Bootstrapped prefLabel from legacy name field |
| 20,684 | bootstrap_labels | name | [2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol | — | Purged legacy name field to enforce prefLabel usage |
| 20,685 | bootstrap_labels | synonyms | ["organic","1h-imidazole-5-methanol,2-butyl-4-chloro-1-[[2'","-(2h-tetrazol-5-yl)[1,1'","-biphenyl]-4-yl]methyl… | [] | Removed legacy synonyms field in favor of structured labels |
| 69,138 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 69,139 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 79,952 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 79,953 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 80,836 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 80,837 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 84,072 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Ocean"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 84,073 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-ocea | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 101,988 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Medium stack, <150 meters","population_density":"Rural (<1000 peop… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 101,989 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-mest15me-ru10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 116,302 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 116,303 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 124,892 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Ground level","population_density":"Urban (>1000 people/square mil… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 124,893 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-grle-ur10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 130,996 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 130,997 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 142,472 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 142,473 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 144,212 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 144,213 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-agri | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 167,062 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","indoor":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 167,063 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-indr-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 194,040 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 194,041 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 202,334 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Non-agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 202,335 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-noag | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 220,022 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 246,244 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 246,245 | enrich_references | skos_definition | — | [{"@value":"A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisu… | Merged ChEBI/PubChem definitions into skos:definition |
| 246,246 | enrich_references | references | [] | [{"@id":"drugcentral:1610","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":"… | Added references with provenance; cas_numbers=['114798-26-4']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_6541']; candidate_pubchem_cids=[3961, 24848371, 29934697]; selected_pubchem_cids=[3961]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 253,817 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | rdkit_pre_consensus from 'CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl'; added: monoisotopic_mass |
| 257,026 | chebi_altlabels | altLabel | [] | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | Added 5 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 263,427 | consensus_match | prefLabel | [{"@value":"[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol","@lan… | [{"@value":"Losartan","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttributedTo":"consen… | cas=114798-26-4; cc_chebi_agreed_name='Losartan'; object_uuid=fo-71d33d9cf32dbbc6 |
| 263,428 | consensus_match | altLabel | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | cas=114798-26-4; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-71d33d9cf32dbbc6 |
| 263,429 | consensus_match | altLabel | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | group_key=[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol||dimension=Environmental > media=Water > water_body=Long-term; cas=114798-26-4; added Common Chemistry CAS names as altLabel: 1-[1-[[2′-(2<em>H</em>-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-butyl-4-chloro-1<em>H</em>-imidazol-5-yl]methanol, 1<em>H</em>-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2′-(1<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, 1<em>H</em>-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2′-(2<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, 2-Butyl-4-chloro-1-[[2′-(1<em>H</em>-tetrazol-5-yl)-1,1′-biphenyl-4-yl]methyl]-1<em>H</em>-imidazole-5-methanol, 2-Butyl-4-chloro-1-[[2′-(2<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1<em>H</em>-imidazole-5-methanol, Allisartan, Angizaar, DUP 89, Lortaan, Lozap, MeSH ID: D019808, Xartan, [2-Butyl-4-chloro-1-([4-[2-(1<em>H</em>-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1<em>H</em>-imidazol-5-yl]methanol, [2-Butyl-5-chloro-3-[2′-(2<em>H</em>-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3<em>H</em>-imidazol-4-yl]-methanol, [2-Butyl-5-chloro-3-[[4-[2-(2<em>H</em>-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol; object_uuid=fo-71d33d9cf32dbbc6 |
| 263,430 | consensus_match | cas_match_labels | — | {"114798-26-4":"exactMatch"} | group_key=[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol||dimension=Environmental > media=Water > water_body=Long-term; group_sources=['chebi', 'pubchem']; cas_sources={'114798-26-4': ['chebi', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-71d33d9cf32dbbc6: {'114798-26-4': 'exactMatch'} |
| 279,019 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol' |
| 285,846 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | rdkit_post_consensus from 'CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 291,362 | strip_catalogue_altlabels | altLabel | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | Removed 1 catalogue altLabel value(s): 'DUP 89' (grade code) |
| 315,586 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/311340d1-18e9-… | associations resolved on the elementary layer |
| 320,989 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/40b2b8c2-67b7-… | associations resolved on the elementary layer |
| 321,431 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/42519757-c2f6-… | associations resolved on the elementary layer |
| 323,050 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/47e6bdfe-022b-… | associations resolved on the elementary layer |
| 331,991 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/57d543ec-4457-… | associations resolved on the elementary layer |
| 339,150 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/6fae28e0-c220-… | associations resolved on the elementary layer |
| 343,448 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/7e41cdfc-ad2f-… | associations resolved on the elementary layer |
| 346,498 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/88a7e551-9cb0-… | associations resolved on the elementary layer |