Sotalol hydrochloride
Everything that changed this substance, across every flow that resolves to it. Back to the substance
fo-93a950a1d18a3f5d
Changes
58| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 4,341 | bootstrap_labels | prefLabel | — | [{"@value":"4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide hydrochloride","@language":"en","source":{"prov:w… | Bootstrapped prefLabel from legacy name field |
| 4,342 | bootstrap_labels | name | 4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide hydrochloride | — | Purged legacy name field to enforce prefLabel usage |
| 4,343 | bootstrap_labels | synonyms | ["organic","4'","-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilidehydrochloride"] | [] | Removed legacy synonyms field in favor of structured labels |
| 29,760 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","indoor":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 29,761 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-indr-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, indoor |
| 30,096 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 30,097 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 49,748 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 49,749 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified |
| 76,568 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 76,569 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-agri | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to agricultural soil |
| 76,608 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 76,609 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 76,928 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 76,929 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 85,984 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Ocean"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 85,985 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-ocea | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to sea water |
| 123,542 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Medium stack, <150 meters","population_density":"Rural (<1000 peop… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 123,543 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-mest15me-ru10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to non-urban air or from high stacks |
| 137,518 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Ground level","population_density":"Urban (>1000 people/square mil… | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 137,519 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-grle-ur10pesq | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to urban air close to ground |
| 151,868 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 151,869 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 154,384 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Non-agricultural"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 154,385 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-noag | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to non-agricultural soil |
| 157,646 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 157,647 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 171,414 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 171,415 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified |
| 214,789 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 222,093 | normalize_name_case | prefLabel | [{"@value":"4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide hydrochloride","@language":"en","source":{"prov:w… | [{"@value":"4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide Hydrochloride","@language":"en","source":{"prov:w… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 231,355 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H20N2O3… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 231,356 | enrich_references | skos_definition | — | [{"@value":"A hydrochloride salt that is the monohydrochloride of sotalol. It has both β-adrenoreceptor blocking (Vaugh… | Merged ChEBI/PubChem definitions into skos:definition |
| 231,357 | enrich_references | references | [] | [{"@id":"https://chem.echa.europa.eu/100.012.269","provenance":{"prov:wasGeneratedBy":"enrich_references.pubchem_identi… | Added references with provenance; cas_numbers=['959-24-0']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_9207']; candidate_pubchem_cids=[5253, 66245, 165245, 67108155]; selected_pubchem_cids=[66245]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 249,519 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H20N2O3… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H20N2O3… | rdkit_pre_consensus from 'CC(C)NCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.Cl'; added: monoisotopic_mass |
| 254,925 | chebi_altlabels | altLabel | [] | [{"@value":"4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride","@language":"en","source":{"p… | Added 10 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 262,259 | consensus_match | prefLabel | [{"@value":"4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilide Hydrochloride","@language":"en","source":{"prov:w… | [{"@value":"Sotalol hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttribut… | cas=959-24-0; cc_chebi_agreed_name='Sotalol hydrochloride'; object_uuid=fo-93a950a1d18a3f5d |
| 262,260 | consensus_match | altLabel | [{"@value":"4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride","@language":"en","source":{"p… | [{"@value":"4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride","@language":"en","source":{"p… | cas=959-24-0; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-93a950a1d18a3f5d |
| 262,261 | consensus_match | altLabel | [{"@value":"4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride","@language":"en","source":{"p… | [{"@value":"4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride","@language":"en","source":{"p… | group_key=4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilidehydrochloride||dimension=Environmental > media=Air > indoor=Unknown; cas=959-24-0; added Common Chemistry CAS names as altLabel: (±)-Sotalol hydrochloride, 4′-[1-Hydroxy-2-(isopropylamino)ethyl]methanesulfonanilide hydrochloride, 4′-[2-(Isopropylamino)-1-hydroxyethyl]methanesulfonanilide hydrochloride, 4′-[2-(Isopropylamino)-1-hydroxyethyl]methanesulfonanilide monohydrochloride, <em>N</em>-Isopropyl-β-(4-methanesulfonamidophenyl)ethanolamine hydrochloride, <em>N</em>-[4-[1-Hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]methanesulfonamide hydrochloride, <em>dl</em>-Sotalol hydrochloride, <span class="text-smallcaps">D</smallcap><smallcap>L</span>-MJ 1999, Darob, MJ 1999, Methanesulfonamide, <em>N</em>-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-, hydrochloride (1:1), Methanesulfonamide, <em>N</em>-[4-[1-hydroxy-2-[(1-methylethyl)amino]ethyl]phenyl]-, monohydrochloride, Methanesulfonanilide, 4′-[1-hydroxy-2-(isopropylamino)ethyl]-, monohydrochloride, Sotacor, Sotalex; object_uuid=fo-93a950a1d18a3f5d |
| 262,262 | consensus_match | cas_match_labels | — | {"959-24-0":"exactMatch"} | group_key=4'-(1-hydroxy-2-isopropylaminoethyl)methanesulphonanilidehydrochloride||dimension=Environmental > media=Air > indoor=Unknown; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'959-24-0': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-93a950a1d18a3f5d: {'959-24-0': 'exactMatch'} |
| 274,650 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H20N2O3… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H20N2O3… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride' |
| 281,106 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H20N2O3… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C12H20N2O3… | rdkit_post_consensus from 'CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1.Cl'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 288,142 | strip_catalogue_altlabels | altLabel | [{"@value":"4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride","@language":"en","source":{"p… | [{"@value":"4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride","@language":"en","source":{"p… | Removed 1 catalogue altLabel value(s): 'MJ 1999' (grade code) |
| 295,919 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/050008ae-f31d-… | associations resolved on the elementary layer |
| 296,087 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/05a1b077-f34e-… | associations resolved on the elementary layer |
| 305,901 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/14f720b2-395e-… | associations resolved on the elementary layer |
| 319,299 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/3c91862f-8d84-… | associations resolved on the elementary layer |
| 319,319 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/3ca312b5-8f75-… | associations resolved on the elementary layer |
| 319,479 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/3d2b8912-c54a-… | associations resolved on the elementary layer |
| 324,007 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/4b6855dd-fca3-… | associations resolved on the elementary layer |