Betamethasone
Everything that changed this flow. Back to the flow
6026432c-a4e6-4998-a269-7fda4846f58e
By field
13 fields| Field | Changes | Written by | Latest note |
|---|---|---|---|
| properties | 6 | enrich_references, link_flows_to_their_substance, normalise_property_values, opsin_iupac, rdkit_post_consensus, rdkit_pre_consensus | the substance's answer, copied onto its flow |
| altLabel | 4 | chebi_altlabels, consensus_match, strip_catalogue_altlabels | Removed 2 catalogue altLabel value(s): 'NSC 39470' (registry code), 'Sch 4831' (grade code) |
| prefLabel | 2 | bootstrap_labels, consensus_match | cas=378-44-9; cc_chebi_agreed_name='Betamethasone'; object_uuid=fo-173c4385260d38e2 |
| cas_match_labels | 1 | consensus_match | group_key=9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-methylpregna-1,4-diene-3,20-dione||dimension=Environmental > media=Water > water_body=Surface water; group_sources=['chebi', 'ec_inventory']; cas_sources={'378-44-9': ['chebi', 'ec_inventory']}; assigned CAS labels from group consensus; object_uuid=fo-173c4385260d38e2: {'378-44-9': 'exactMatch'} |
| concept_associations | 1 | carry_associations_onto_flows | associations resolved on the elementary layer |
| context | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| context_iri | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| name | 1 | bootstrap_labels | Purged legacy name field to enforce prefLabel usage |
| references | 1 | enrich_references | Added references with provenance; cas_numbers=['378-44-9']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_3077']; candidate_pubchem_cids=[3003, 9782, 91620, 146364, 969487, 5702012, 6546942, 6710614, 11014684, 12358601, 13075978, 21140858, 40469538, 71299643, 121231050, 123133873, 133634290, 145705940, 163198893, 163285078, 171035078, 176541415]; selected_pubchem_cids=[9782]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| skos_definition | 1 | enrich_references | Merged ChEBI/PubChem definitions into skos:definition |
| synonyms | 1 | bootstrap_labels | Removed legacy synonyms field in favor of structured labels |
| types | 1 | link_flows_to_their_substance | the substance's answer, copied onto its flow |
| unit_iri | 1 | unit_normalization | Unit IRI set from normalization of 'kg' |
Where several steps wrote one field, the last one won — and the log below shows the sequence.
Changes
22| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 18,435 | bootstrap_labels | prefLabel | — | [{"@value":"9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-meth… | Bootstrapped prefLabel from legacy name field |
| 18,436 | bootstrap_labels | name | 9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-methylpregna-1,4… | — | Purged legacy name field to enforce prefLabel usage |
| 18,437 | bootstrap_labels | synonyms | ["betamethasone","(1r,2s,10s,11s,13s,14r,15s,17s)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetrac… | [] | Removed legacy synonyms field in favor of structured labels |
| 106,902 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Ground","geography":"Unknown"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 106,903 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-grou-unkn | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to soil > Emissions to soil, unspecified |
| 219,365 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 244,401 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 244,402 | enrich_references | skos_definition | — | [] | Merged ChEBI/PubChem definitions into skos:definition |
| 244,403 | enrich_references | references | [] | [{"@id":"beilstein:3176546","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":… | Added references with provenance; cas_numbers=['378-44-9']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_3077']; candidate_pubchem_cids=[3003, 9782, 91620, 146364, 969487, 5702012, 6546942, 6710614, 11014684, 12358601, 13075978, 21140858, 40469538, 71299643, 121231050, 123133873, 133634290, 145705940, 163198893, 163285078, 171035078, 176541415]; selected_pubchem_cids=[9782]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 253,280 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | rdkit_pre_consensus from 'CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C'; added: inchi2d_string, monoisotopic_mass |
| 256,798 | chebi_altlabels | altLabel | [] | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | Added 10 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 263,371 | consensus_match | prefLabel | [{"@value":"9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-meth… | [{"@value":"Betamethasone","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttributedTo":"c… | cas=378-44-9; cc_chebi_agreed_name='Betamethasone'; object_uuid=fo-173c4385260d38e2 |
| 263,372 | consensus_match | altLabel | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | cas=378-44-9; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-173c4385260d38e2 |
| 263,373 | consensus_match | altLabel | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | group_key=9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-methylpregna-1,4-diene-3,20-dione||dimension=Environmental > media=Water > water_body=Surface water; cas=378-44-9; added Common Chemistry CAS names as altLabel: (11β,16β)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9-Fluoro-16β-methylprednisolone, 9α-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-11β,17α,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-16β-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 9α-Fluoro-16β-methylprednisolone, Becort, Bedifos, Betacorlan, Betacortil, Betacortril, Betametasone, Betamethazone, Betapredol, Betasolon, Bethamethasone, Betnelan, Betsolan, Bifas, Celestan, Celestene, Celeston, Celestone, Cidoten, Colircusi betamida, Dermabet, Desacort-Beta, Ethamethasoneb, Flosteron, Flubenisolone, MeSH ID: D001623, NSC 39470, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11β,16β)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16β-methyl-, Rinderon A, Sch 4831, Visubeta, β-Methasone, β-Methasone alcohol; object_uuid=fo-173c4385260d38e2 |
| 263,374 | consensus_match | cas_match_labels | — | {"378-44-9":"exactMatch"} | group_key=9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione/n9a-fluoro-11ß,17a,21-trihydroxy-16ß-methylpregna-1,4-diene-3,20-dione||dimension=Environmental > media=Water > water_body=Surface water; group_sources=['chebi', 'ec_inventory']; cas_sources={'378-44-9': ['chebi', 'ec_inventory']}; assigned CAS labels from group consensus; object_uuid=fo-173c4385260d38e2: {'378-44-9': 'exactMatch'} |
| 278,490 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione' |
| 285,256 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | rdkit_post_consensus from 'C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 290,962 | strip_catalogue_altlabels | altLabel | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | [{"@value":"16beta-Methyl-1,4-pregnadiene-9alpha-fluoro-11beta,17alpha,21-triol-3,20-dione","@language":"en","source":{… | Removed 2 catalogue altLabel value(s): 'NSC 39470' (registry code), 'Sch 4831' (grade code) |
| 334,449 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/6026432c-a4e6-… | associations resolved on the elementary layer |
| 392,858 | normalise_property_values | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | typed the way the ontology types it |
| 401,525 | link_flows_to_their_substance | types | — | ["https://w3id.org/chemrof/NeutralMolecule"] | the substance's answer, copied onto its flow |
| 401,526 | link_flows_to_their_substance | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | the substance's answer, copied onto its flow |
PROV-O trail
22 activitiesOne activity per change: which version of the flow it consumed, and which it produced. The values are on the change with the same number — stored once, not twice.
| Activity | Field | Agent | Used | Generated |
|---|---|---|---|---|
| ef:activity/change/20260821T1554374006150000/18435 | prefLabel | ef:agent/bootstrap_labels | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v0 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v1 |
| ef:activity/change/20260821T1554374006150000/18436 | name | ef:agent/bootstrap_labels | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v1 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v2 |
| ef:activity/change/20260821T1554374006150000/18437 | synonyms | ef:agent/bootstrap_labels | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v2 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v3 |
| ef:activity/change/20260821T1554374006150000/106902 | context | ef:agent/default_context_mapping | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v3 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v4 |
| ef:activity/change/20260821T1554374006150000/106903 | context_iri | ef:agent/default_context_mapping | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v4 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v5 |
| ef:activity/change/20260821T1554374006150000/219365 | unit_iri | ef:agent/unit_normalization | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v5 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v6 |
| ef:activity/change/20260821T1554374006150000/244401 | properties | ef:agent/enrich_references | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v6 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v7 |
| ef:activity/change/20260821T1554374006150000/244402 | skos_definition | ef:agent/enrich_references | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v7 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v8 |
| ef:activity/change/20260821T1554374006150000/244403 | references | ef:agent/enrich_references | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v8 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v9 |
| ef:activity/change/20260821T1554374006150000/253280 | properties | ef:agent/rdkit_pre_consensus | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v9 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v10 |
| ef:activity/change/20260821T1554374006150000/256798 | altLabel | ef:agent/chebi_altlabels | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v10 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v11 |
| ef:activity/change/20260821T1554374006150000/263371 | prefLabel | ef:agent/consensus_match | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v11 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v12 |
| ef:activity/change/20260821T1554374006150000/263372 | altLabel | ef:agent/consensus_match | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v12 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v13 |
| ef:activity/change/20260821T1554374006150000/263373 | altLabel | ef:agent/consensus_match | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v13 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v14 |
| ef:activity/change/20260821T1554374006150000/263374 | cas_match_labels | ef:agent/consensus_match | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v14 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v15 |
| ef:activity/change/20260821T1554374006150000/278490 | properties | ef:agent/opsin_iupac | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v15 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v16 |
| ef:activity/change/20260821T1554374006150000/285256 | properties | ef:agent/rdkit_post_consensus | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v16 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v17 |
| ef:activity/change/20260821T1554374006150000/290962 | altLabel | ef:agent/strip_catalogue_altlabels | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v17 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v18 |
| ef:activity/change/20260821T1554374006150000/334449 | concept_associations | ef:agent/carry_associations_onto_flows | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v18 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v19 |
| ef:activity/change/20260821T1554374006150000/392858 | properties | ef:agent/normalise_property_values | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v19 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v20 |
| ef:activity/change/20260821T1554374006150000/401525 | types | ef:agent/link_flows_to_their_substance | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v20 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v21 |
| ef:activity/change/20260821T1554374006150000/401526 | properties | ef:agent/link_flows_to_their_substance | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v21 | ef:flow/6026432c-a4e6-4998-a269-7fda4846f58e/v22 |