Dexamethasone
Everything that changed this flow. Back to the flow
9189dd06-324c-46fd-a58b-256db78ca7cc
By field
14 fields| Field | Changes | Written by | Latest note |
|---|---|---|---|
| properties | 6 | enrich_references, link_flows_to_their_substance, normalise_property_values, opsin_iupac, rdkit_post_consensus, rdkit_pre_consensus | the substance's answer, copied onto its flow |
| altLabel | 3 | chebi_altlabels, consensus_match, strip_catalogue_altlabels | Removed 4 catalogue altLabel value(s): 'AVM 0703' (grade code), 'MK 125' (grade code), 'NSC 34521' (registry code), 'OCS 01' (grade code) |
| prefLabel | 2 | bootstrap_labels, normalize_name_case | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| cas_match_labels | 1 | consensus_match | group_key=dexamethasone||dimension=Environmental > media=Water > water_body=Surface water; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'50-02-2': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-0c357899caef61e8: {'50-02-2': 'exactMatch'} |
| concept_associations | 1 | carry_associations_onto_flows | associations resolved on the elementary layer |
| context | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| context_iri | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| name | 1 | bootstrap_labels | Purged legacy name field to enforce prefLabel usage |
| references | 1 | enrich_references | Added references with provenance; cas_numbers=['50-02-2']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_41879']; candidate_pubchem_cids=[3003, 5743, 9782, 451600, 5702035, 6610335, 9830630, 12358601, 71308592, 139033726, 145705940, 163285103, 171036213]; selected_pubchem_cids=[5743]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| roles | 1 | link_flows_to_their_substance | the substance's answer, copied onto its flow |
| skos_definition | 1 | enrich_references | Merged ChEBI/PubChem definitions into skos:definition |
| synonyms | 1 | bootstrap_labels | Removed legacy synonyms field in favor of structured labels |
| types | 1 | link_flows_to_their_substance | the substance's answer, copied onto its flow |
| unit_iri | 1 | unit_normalization | Unit IRI set from normalization of 'kg' |
Where several steps wrote one field, the last one won — and the log below shows the sequence.
Changes
22| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 3,840 | bootstrap_labels | prefLabel | — | [{"@value":"dexamethasone","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"… | Bootstrapped prefLabel from legacy name field |
| 3,841 | bootstrap_labels | name | dexamethasone | — | Purged legacy name field to enforce prefLabel usage |
| 3,842 | bootstrap_labels | synonyms | ["organic","dexamethasone"] | [] | Removed legacy synonyms field in favor of structured labels |
| 136,231 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 136,232 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 214,627 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 221,979 | normalize_name_case | prefLabel | [{"@value":"dexamethasone","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"… | [{"@value":"Dexamethasone","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttributedTo":"… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 230,889 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 230,890 | enrich_references | skos_definition | — | [{"@value":"A fluorinated steroid that is 9-fluoropregna-1,4-diene substituted by hydroxy groups at positions 11, 17 an… | Merged ChEBI/PubChem definitions into skos:definition |
| 230,891 | enrich_references | references | [] | [{"@id":"beilstein:2066652","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":… | Added references with provenance; cas_numbers=['50-02-2']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_41879']; candidate_pubchem_cids=[3003, 5743, 9782, 451600, 5702035, 6610335, 9830630, 12358601, 71308592, 139033726, 145705940, 163285103, 171036213]; selected_pubchem_cids=[5743]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 249,395 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | rdkit_pre_consensus from 'CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C'; added: inchi2d_string, monoisotopic_mass |
| 254,876 | chebi_altlabels | altLabel | [] | [{"@value":"(11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione","@language":"en","sourc… | Added 32 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 265,621 | consensus_match | altLabel | [{"@value":"(11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione","@language":"en","sourc… | [{"@value":"(11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione","@language":"en","sourc… | group_key=dexamethasone||dimension=Environmental > media=Water > water_body=Surface water; cas=50-02-2; added Common Chemistry CAS names as altLabel: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, 1-Dehydro-16α-methyl-9α-fluorohydrocortisone, 16α-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 16α-Methyl-9α-fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione, 16α-Methyl-9α-fluoro-Δ<sup>1</sup>-hydrocortisone, 16α-Methyl-9α-fluoroprednisolone, 24: PN: US20220380460 SEQID: 25 claimed sequence, 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione, 9α-Fluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione, 9α-Fluoro-16α-methyl-1,4-pregnadiene-11β,17α,21-triol-3,20-dione, 9α-Fluoro-16α-methyl-11β,17,21-trihydroxypregna-1,4-diene-3,20-dione, 9α-Fluoro-16α-methylprednisolone, AVM 0703, Adexone, Aphtasolon, Aphthasolone, Corsone, DEX, De-Sone LA, Decaderm, Decadron A, Decasone, Dekacort, Dekort, Delipos, Deltafluorene, Dergramin, Deronil, Desadrene, Desameton, Deseronil, Dexa-Cortidelt, Dexa-Mamallet, Dexa-Scheroson, Dexa-sine, Dexacort, Dexadeltone, Dexafarma, Dexalona, Dexaltin, Dexameth, Dexamethasone alcohol, Dexamonozon, Dexapolcort, Dexapos, Dexaprol, Dexaratiopharm, Dexaven, Dexinoral, Dexium, Dexmethsone, Dexone, Dexonium, Dextelan, Dextenza, Dinormon, Dxevo, Etacortilen, Fluormone, Fluorocort, Gammacorten, Gentalipos, HL-Dex, Hexadecadrol, Isopto-Dex, Lokalison F, Loverine, Luxazone, MK 125, MeSH ID: D003907, Minidex, NSC 34521, Neofordex, OCS 01, Oftan, Pet-Derm III, Posurdex, Prednisolon F, Prednisolone F, Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11β,16α)-, Pregna-1,4-diene-3,20-dione, 9-fluoro-11β,17,21-trihydroxy-16α-methyl-, Superprednol, Surodex, Visumetazone; object_uuid=fo-0c357899caef61e8 |
| 265,622 | consensus_match | cas_match_labels | — | {"50-02-2":"exactMatch"} | group_key=dexamethasone||dimension=Environmental > media=Water > water_body=Surface water; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'50-02-2': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-0c357899caef61e8: {'50-02-2': 'exactMatch'} |
| 274,528 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '(11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione' |
| 280,971 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | rdkit_post_consensus from 'C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 288,059 | strip_catalogue_altlabels | altLabel | [{"@value":"(11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione","@language":"en","sourc… | [{"@value":"(11beta,16alpha)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione","@language":"en","sourc… | Removed 4 catalogue altLabel value(s): 'AVM 0703' (grade code), 'MK 125' (grade code), 'NSC 34521' (registry code), 'OCS 01' (grade code) |
| 349,148 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/9189dd06-324c-… | associations resolved on the elementary layer |
| 388,853 | normalise_property_values | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | typed the way the ontology types it |
| 395,743 | link_flows_to_their_substance | types | — | ["https://w3id.org/chemrof/NeutralMolecule"] | the substance's answer, copied onto its flow |
| 395,744 | link_flows_to_their_substance | roles | — | [{"@id":"http://purl.obolibrary.org/obo/CHEBI_78298","rdfs:label":"environmental contaminant","http://www.w3.org/2004/0… | the substance's answer, copied onto its flow |
| 395,745 | link_flows_to_their_substance | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H29FO5"… | the substance's answer, copied onto its flow |
PROV-O trail
22 activitiesOne activity per change: which version of the flow it consumed, and which it produced. The values are on the change with the same number — stored once, not twice.
| Activity | Field | Agent | Used | Generated |
|---|---|---|---|---|
| ef:activity/change/20261019T0712047113160000/3840 | prefLabel | ef:agent/bootstrap_labels | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v0 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v1 |
| ef:activity/change/20261019T0712047113160000/3841 | name | ef:agent/bootstrap_labels | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v1 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v2 |
| ef:activity/change/20261019T0712047113160000/3842 | synonyms | ef:agent/bootstrap_labels | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v2 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v3 |
| ef:activity/change/20261019T0712047113160000/136231 | context | ef:agent/default_context_mapping | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v3 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v4 |
| ef:activity/change/20261019T0712047113160000/136232 | context_iri | ef:agent/default_context_mapping | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v4 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v5 |
| ef:activity/change/20261019T0712047113160000/214627 | unit_iri | ef:agent/unit_normalization | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v5 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v6 |
| ef:activity/change/20261019T0712047113160000/221979 | prefLabel | ef:agent/normalize_name_case | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v6 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v7 |
| ef:activity/change/20261019T0712047113160000/230889 | properties | ef:agent/enrich_references | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v7 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v8 |
| ef:activity/change/20261019T0712047113160000/230890 | skos_definition | ef:agent/enrich_references | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v8 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v9 |
| ef:activity/change/20261019T0712047113160000/230891 | references | ef:agent/enrich_references | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v9 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v10 |
| ef:activity/change/20261019T0712047113160000/249395 | properties | ef:agent/rdkit_pre_consensus | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v10 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v11 |
| ef:activity/change/20261019T0712047113160000/254876 | altLabel | ef:agent/chebi_altlabels | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v11 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v12 |
| ef:activity/change/20261019T0712047113160000/265621 | altLabel | ef:agent/consensus_match | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v12 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v13 |
| ef:activity/change/20261019T0712047113160000/265622 | cas_match_labels | ef:agent/consensus_match | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v13 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v14 |
| ef:activity/change/20261019T0712047113160000/274528 | properties | ef:agent/opsin_iupac | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v14 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v15 |
| ef:activity/change/20261019T0712047113160000/280971 | properties | ef:agent/rdkit_post_consensus | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v15 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v16 |
| ef:activity/change/20261019T0712047113160000/288059 | altLabel | ef:agent/strip_catalogue_altlabels | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v16 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v17 |
| ef:activity/change/20261019T0712047113160000/349148 | concept_associations | ef:agent/carry_associations_onto_flows | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v17 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v18 |
| ef:activity/change/20261019T0712047113160000/388853 | properties | ef:agent/normalise_property_values | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v18 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v19 |
| ef:activity/change/20261019T0712047113160000/395743 | types | ef:agent/link_flows_to_their_substance | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v19 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v20 |
| ef:activity/change/20261019T0712047113160000/395744 | roles | ef:agent/link_flows_to_their_substance | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v20 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v21 |
| ef:activity/change/20261019T0712047113160000/395745 | properties | ef:agent/link_flows_to_their_substance | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v21 | ef:flow/9189dd06-324c-46fd-a58b-256db78ca7cc/v22 |