Metformin hydrochloride
Everything that changed this flow. Back to the flow
e6026eec-c590-4dca-9d61-efaf6ccf4156
By field
14 fields| Field | Changes | Written by | Latest note |
|---|---|---|---|
| properties | 5 | enrich_references, normalise_property_values, opsin_iupac, rdkit_post_consensus, rdkit_pre_consensus | typed the way the ontology types it |
| altLabel | 4 | chebi_altlabels, consensus_match, strip_catalogue_altlabels | Removed 2 catalogue altLabel value(s): 'Glucophage 850' (trade name), 'LA 6023' (grade code) |
| prefLabel | 3 | bootstrap_labels, consensus_match, normalize_name_case | cas=1115-70-4; cc_chebi_agreed_name='Metformin hydrochloride'; object_uuid=fo-1a04206c4c57d38b |
| cas_match_labels | 1 | consensus_match | group_key=n,n-dimethylimidodicarbonimidicdiamidehydrochloride||dimension=Environmental > media=Water > water_body=Ocean; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'1115-70-4': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-1a04206c4c57d38b: {'1115-70-4': 'exactMatch'} |
| concept_associations | 1 | carry_associations_onto_flows | associations resolved on the elementary layer |
| context | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| context_iri | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| name | 1 | bootstrap_labels | Purged legacy name field to enforce prefLabel usage |
| references | 1 | enrich_references | Added references with provenance; cas_numbers=['1115-70-4']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_6802']; candidate_pubchem_cids=[14219, 20585394, 53630812, 137346479, 137704554, 152743144, 155906370, 176517462]; selected_pubchem_cids=[14219]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| roles | 1 | link_flows_to_their_substance | the substance's answer, copied onto its flow |
| skos_definition | 1 | enrich_references | Merged ChEBI/PubChem definitions into skos:definition |
| synonyms | 1 | bootstrap_labels | Removed legacy synonyms field in favor of structured labels |
| types | 1 | link_flows_to_their_substance | the substance's answer, copied onto its flow |
| unit_iri | 1 | unit_normalization | Unit IRI set from normalization of 'kg' |
Where several steps wrote one field, the last one won — and the log below shows the sequence.
Changes
23| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 13,739 | bootstrap_labels | prefLabel | — | [{"@value":"n,n-dimethylimidodicarbonimidic diamide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"bo… | Bootstrapped prefLabel from legacy name field |
| 13,740 | bootstrap_labels | name | n,n-dimethylimidodicarbonimidic diamide hydrochloride | — | Purged legacy name field to enforce prefLabel usage |
| 13,741 | bootstrap_labels | synonyms | ["organic","metforminhydrochloride"] | [] | Removed legacy synonyms field in favor of structured labels |
| 187,506 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Surface water"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 187,507 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-suwa | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to fresh water |
| 217,878 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 224,275 | normalize_name_case | prefLabel | [{"@value":"n,n-dimethylimidodicarbonimidic diamide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"bo… | [{"@value":"N,n-dimethylimidodicarbonimidic Diamide Hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"bo… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 240,194 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 240,195 | enrich_references | skos_definition | — | [{"@value":"A hydrochloride resulting from the reaction of metformin with one molar equivalent of hydrogen chloride.","… | Merged ChEBI/PubChem definitions into skos:definition |
| 240,196 | enrich_references | references | [] | [{"@id":"https://chem.echa.europa.eu/100.012.937","provenance":{"prov:wasGeneratedBy":"enrich_references.pubchem_identi… | Added references with provenance; cas_numbers=['1115-70-4']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_6802']; candidate_pubchem_cids=[14219, 20585394, 53630812, 137346479, 137704554, 152743144, 155906370, 176517462]; selected_pubchem_cids=[14219]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 252,062 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | rdkit_pre_consensus from 'CN(C)C(=N)N=C(N)N.Cl'; added: monoisotopic_mass |
| 256,239 | chebi_altlabels | altLabel | [] | [{"@value":"1,1-Dimethylbiguanide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels","pr… | Added 9 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 269,231 | consensus_match | prefLabel | [{"@value":"N,n-dimethylimidodicarbonimidic Diamide Hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"bo… | [{"@value":"Metformin hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttrib… | cas=1115-70-4; cc_chebi_agreed_name='Metformin hydrochloride'; object_uuid=fo-1a04206c4c57d38b |
| 269,232 | consensus_match | altLabel | [{"@value":"1,1-Dimethylbiguanide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels","pr… | [{"@value":"1,1-Dimethylbiguanide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels","pr… | cas=1115-70-4; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-1a04206c4c57d38b |
| 269,233 | consensus_match | altLabel | [{"@value":"1,1-Dimethylbiguanide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels","pr… | [{"@value":"1,1-Dimethylbiguanide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels","pr… | group_key=n,n-dimethylimidodicarbonimidicdiamidehydrochloride||dimension=Environmental > media=Water > water_body=Ocean; cas=1115-70-4; added Common Chemistry CAS names as altLabel: <em>N</em>,<em>N</em>-Dimethylbiguanidine monohydrochloride, <em>N</em>,<em>N</em>-Dimethylbiguanidinium chloride, <em>N</em><sup>1</sup>,<em>N</em><sup>1</sup>-Dimethylbiguanide hydrochloride, Apo-Metformin, Apophage, Benofomin, Biguanide, 1,1-dimethyl-, hydrochloride, Biguanide, 1,1-dimethyl-, monohydrochloride, Brot, Dabex, Denkaform, Dextin, Diabefagos, Diabetmim, Diabetmin, Diabetosan, Diabex, Diaformin, Dialon, Diformin, Diformin Retard, Dimefor, FORTAMET, Fornidd, Geamet, Glifage, Glucaminol, Glucofago, Glucoform, Glucoformin, Glucomet, Glucomin, Glucomine, Gluconil, Glucophage 850, Glucophage Forte, Glucophage Retard, Glucophage SR, Glucophage XR, Glucophage-Mite, Gludepatic, Glufor, Gluformin, Glumeformin, Glumetza, Glumin, Glumin XR, Glupermin, Glyceriphage, Glyciphage, Glycon, Glyformin, Imidodicarbonimidic diamide, <em>N</em>,<em>N</em>-dimethyl-, hydrochloride (1:1), Imidodicarbonimidic diamide, <em>N</em>,<em>N</em>-dimethyl-, monohydrochloride, LA 6023, Meguan, Melbin, Metforal, Metgluco, Metomin, Miformin, Nelbis, Neodipa, Obimat-SR, Orabet, Riomet, Siamformet, Walaphage; object_uuid=fo-1a04206c4c57d38b |
| 269,234 | consensus_match | cas_match_labels | — | {"1115-70-4":"exactMatch"} | group_key=n,n-dimethylimidodicarbonimidicdiamidehydrochloride||dimension=Environmental > media=Water > water_body=Ocean; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'1115-70-4': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-1a04206c4c57d38b: {'1115-70-4': 'exactMatch'} |
| 277,260 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '1,1-Dimethylbiguanide hydrochloride' |
| 283,927 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | rdkit_post_consensus from 'CN(C)C(=N)NC(=N)N.Cl'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 290,078 | strip_catalogue_altlabels | altLabel | [{"@value":"1,1-Dimethylbiguanide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels","pr… | [{"@value":"1,1-Dimethylbiguanide hydrochloride","@language":"en","source":{"prov:wasGeneratedBy":"chebi_altlabels","pr… | Removed 2 catalogue altLabel value(s): 'Glucophage 850' (trade name), 'LA 6023' (grade code) |
| 374,781 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/e6026eec-c590-… | associations resolved on the elementary layer |
| 391,609 | normalise_property_values | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C4H11N5.HC… | typed the way the ontology types it |
| 399,718 | link_flows_to_their_substance | types | — | ["https://w3id.org/chemrof/MolecularComplex"] | the substance's answer, copied onto its flow |
| 399,719 | link_flows_to_their_substance | roles | — | [{"@id":"http://purl.obolibrary.org/obo/CHEBI_78298","rdfs:label":"environmental contaminant","http://www.w3.org/2004/0… | the substance's answer, copied onto its flow |
PROV-O trail
23 activitiesOne activity per change: which version of the flow it consumed, and which it produced. The values are on the change with the same number — stored once, not twice.
| Activity | Field | Agent | Used | Generated |
|---|---|---|---|---|
| ef:activity/change/20260822T0600486828500000/13739 | prefLabel | ef:agent/bootstrap_labels | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v0 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v1 |
| ef:activity/change/20260822T0600486828500000/13740 | name | ef:agent/bootstrap_labels | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v1 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v2 |
| ef:activity/change/20260822T0600486828500000/13741 | synonyms | ef:agent/bootstrap_labels | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v2 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v3 |
| ef:activity/change/20260822T0600486828500000/187506 | context | ef:agent/default_context_mapping | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v3 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v4 |
| ef:activity/change/20260822T0600486828500000/187507 | context_iri | ef:agent/default_context_mapping | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v4 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v5 |
| ef:activity/change/20260822T0600486828500000/217878 | unit_iri | ef:agent/unit_normalization | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v5 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v6 |
| ef:activity/change/20260822T0600486828500000/224275 | prefLabel | ef:agent/normalize_name_case | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v6 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v7 |
| ef:activity/change/20260822T0600486828500000/240194 | properties | ef:agent/enrich_references | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v7 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v8 |
| ef:activity/change/20260822T0600486828500000/240195 | skos_definition | ef:agent/enrich_references | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v8 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v9 |
| ef:activity/change/20260822T0600486828500000/240196 | references | ef:agent/enrich_references | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v9 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v10 |
| ef:activity/change/20260822T0600486828500000/252062 | properties | ef:agent/rdkit_pre_consensus | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v10 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v11 |
| ef:activity/change/20260822T0600486828500000/256239 | altLabel | ef:agent/chebi_altlabels | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v11 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v12 |
| ef:activity/change/20260822T0600486828500000/269231 | prefLabel | ef:agent/consensus_match | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v12 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v13 |
| ef:activity/change/20260822T0600486828500000/269232 | altLabel | ef:agent/consensus_match | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v13 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v14 |
| ef:activity/change/20260822T0600486828500000/269233 | altLabel | ef:agent/consensus_match | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v14 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v15 |
| ef:activity/change/20260822T0600486828500000/269234 | cas_match_labels | ef:agent/consensus_match | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v15 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v16 |
| ef:activity/change/20260822T0600486828500000/277260 | properties | ef:agent/opsin_iupac | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v16 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v17 |
| ef:activity/change/20260822T0600486828500000/283927 | properties | ef:agent/rdkit_post_consensus | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v17 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v18 |
| ef:activity/change/20260822T0600486828500000/290078 | altLabel | ef:agent/strip_catalogue_altlabels | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v18 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v19 |
| ef:activity/change/20260822T0600486828500000/374781 | concept_associations | ef:agent/carry_associations_onto_flows | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v19 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v20 |
| ef:activity/change/20260822T0600486828500000/391609 | properties | ef:agent/normalise_property_values | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v20 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v21 |
| ef:activity/change/20260822T0600486828500000/399718 | types | ef:agent/link_flows_to_their_substance | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v21 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v22 |
| ef:activity/change/20260822T0600486828500000/399719 | roles | ef:agent/link_flows_to_their_substance | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v22 | ef:flow/e6026eec-c590-4dca-9d61-efaf6ccf4156/v23 |