Cortisol
Everything that changed this flow. Back to the flow
efa43def-7f88-4a85-b8e6-b5dba0325ecb
By field
13 fields| Field | Changes | Written by | Latest note |
|---|---|---|---|
| properties | 6 | enrich_references, link_flows_to_their_substance, normalise_property_values, opsin_iupac, rdkit_post_consensus, rdkit_pre_consensus | the substance's answer, copied onto its flow |
| altLabel | 4 | chebi_altlabels, consensus_match, strip_catalogue_altlabels | Removed 3 catalogue altLabel value(s): 'CCN 90306A' (grade code), 'NSC 10483' (registry code), 'U 1851' (grade code) |
| prefLabel | 2 | bootstrap_labels, consensus_match | cas=50-23-7; cc_chebi_agreed_name='Cortisol'; object_uuid=fo-e065b83bb7e5a506 |
| cas_match_labels | 1 | consensus_match | group_key=11,17,21-trihydroxypregn-4-ene-3,20-dione||dimension=Environmental > media=Air > strata=Medium stack, <150 meters > population_density=Rural (<1000 people/square mile); group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'50-23-7': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-e065b83bb7e5a506: {'50-23-7': 'exactMatch'} |
| concept_associations | 1 | carry_associations_onto_flows | associations resolved on the elementary layer |
| context | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| context_iri | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| name | 1 | bootstrap_labels | Purged legacy name field to enforce prefLabel usage |
| references | 1 | enrich_references | Added references with provenance; cas_numbers=['50-23-7']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_17650']; candidate_pubchem_cids=[3640, 5754, 108888, 229860, 657311, 5320346, 7048969, 22841298, 40488894, 71309567, 165944364, 171035840, 176519891]; selected_pubchem_cids=[5754]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| skos_definition | 1 | enrich_references | Merged ChEBI/PubChem definitions into skos:definition |
| synonyms | 1 | bootstrap_labels | Removed legacy synonyms field in favor of structured labels |
| types | 1 | link_flows_to_their_substance | the substance's answer, copied onto its flow |
| unit_iri | 1 | unit_normalization | Unit IRI set from normalization of 'kg' |
Where several steps wrote one field, the last one won — and the log below shows the sequence.
Changes
22| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 19,730 | bootstrap_labels | prefLabel | — | [{"@value":"11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labe… | Bootstrapped prefLabel from legacy name field |
| 19,731 | bootstrap_labels | name | 11,17,21-trihydroxypregn-4-ene-3,20-dione | — | Purged legacy name field to enforce prefLabel usage |
| 19,732 | bootstrap_labels | synonyms | ["organic","hydrocortisone","hydrocortisonacetate","zk5191"] | [] | Removed legacy synonyms field in favor of structured labels |
| 193,008 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Aircraft cruise height"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 193,009 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-aicrhe | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to lower stratosphere and upper troposphere |
| 219,759 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 245,499 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 245,500 | enrich_references | skos_definition | — | [{"@value":"A 17α-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy g… | Merged ChEBI/PubChem definitions into skos:definition |
| 245,501 | enrich_references | references | [] | [{"@id":"beilstein:1354819","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":… | Added references with provenance; cas_numbers=['50-23-7']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_17650']; candidate_pubchem_cids=[3640, 5754, 108888, 229860, 657311, 5320346, 7048969, 22841298, 40488894, 71309567, 165944364, 171035840, 176519891]; selected_pubchem_cids=[5754]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 253,604 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | rdkit_pre_consensus from 'CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O'; added: inchi2d_string, monoisotopic_mass |
| 256,955 | chebi_altlabels | altLabel | [] | [{"@value":"(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"chebi… | Added 15 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 259,361 | consensus_match | prefLabel | [{"@value":"11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labe… | [{"@value":"Cortisol","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttributedTo":"consen… | cas=50-23-7; cc_chebi_agreed_name='Cortisol'; object_uuid=fo-e065b83bb7e5a506 |
| 259,362 | consensus_match | altLabel | [{"@value":"(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"chebi… | [{"@value":"(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"chebi… | cas=50-23-7; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-e065b83bb7e5a506 |
| 259,363 | consensus_match | altLabel | [{"@value":"(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"chebi… | [{"@value":"(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"chebi… | group_key=11,17,21-trihydroxypregn-4-ene-3,20-dione||dimension=Environmental > media=Air > strata=Medium stack, <150 meters > population_density=Rural (<1000 people/square mile); cas=50-23-7; added Common Chemistry CAS names as altLabel: (11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione, 11β,17,21-Trihydroxypregn-4-ene-3,20-dione, 11β,17,21-Trihydroxyprogesterone, 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 11β-Hydroxycortisone, 17α-Hydroxycorticosterone, 29: PN: US20220380460 SEQID: 30 claimed sequence, 4-Pregnene-11β,17α,21-triol-3,20-dione, Acticort, Aeroseb HC, Ala-Cort, Ala-scalp, Alkindi, Anflam, Anti-inflammatory hormone, CCN 90306A, CaldeCort Spray, Cetacort, Cobadex, Cort-Dome, Cortanal, Cortef, Cortenema, Cortenerin, Corticreme, Cortifan, Cortiment, Cortispray, Cortonema, Cortril, Dermacort, Dermocortal, Dermolate, Dihydrocostisone, Dioderm, Domolene-HC, DuoCort, Efcorbin, Efcortelan, Eldecort, Epiderm H, Esiderm H, Evacort, Ficortril, Genacort, HC, Heb-Cort, Hidro-Colisona, Hycort, Hycortol, Hycortole, Hydracort, Hydrasson, Hydro-Adreson, Hydrocort, Hydrocortal, Hydrocorticosterone, Hydrocortin, Hydrocortisyl, Hydrocortone, Hydroskin, Hytone, Hytone lotion, Incortin-H, Infacort, Lacticare HC, MeSH ID: D006854, Medicort, Mildison, NSC 10483, Nucort, Nutracort, Optef, Otosone-F, Penecort, Permicort, Plenadren, Polcort H, Pregn-4-ene-3,20-dione, 11,17,21-trihydroxy-, (11β)-, Proctozone, Sanatison, Scalpicin, Scheroson F, Signef, Synacort, Tarcortin, Texacort, Texacort lotion 25, Timocort, Topicort, Traumaide, U 1851, Zenoxone, dermtex hc, u-cort; object_uuid=fo-e065b83bb7e5a506 |
| 259,364 | consensus_match | cas_match_labels | — | {"50-23-7":"exactMatch"} | group_key=11,17,21-trihydroxypregn-4-ene-3,20-dione||dimension=Environmental > media=Air > strata=Medium stack, <150 meters > population_density=Rural (<1000 people/square mile); group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'50-23-7': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-e065b83bb7e5a506: {'50-23-7': 'exactMatch'} |
| 278,834 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione' |
| 285,628 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | rdkit_post_consensus from 'C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)C(=O)CO'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 291,227 | strip_catalogue_altlabels | altLabel | [{"@value":"(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"chebi… | [{"@value":"(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione","@language":"en","source":{"prov:wasGeneratedBy":"chebi… | Removed 3 catalogue altLabel value(s): 'CCN 90306A' (grade code), 'NSC 10483' (registry code), 'U 1851' (grade code) |
| 377,556 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/efa43def-7f88-… | associations resolved on the elementary layer |
| 393,208 | normalise_property_values | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | typed the way the ontology types it |
| 402,048 | link_flows_to_their_substance | types | — | ["https://w3id.org/chemrof/NeutralMolecule"] | the substance's answer, copied onto its flow |
| 402,049 | link_flows_to_their_substance | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C21H30O5"]… | the substance's answer, copied onto its flow |
PROV-O trail
22 activitiesOne activity per change: which version of the flow it consumed, and which it produced. The values are on the change with the same number — stored once, not twice.
| Activity | Field | Agent | Used | Generated |
|---|---|---|---|---|
| ef:activity/change/20260820T0738569779880000/19730 | prefLabel | ef:agent/bootstrap_labels | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v0 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v1 |
| ef:activity/change/20260820T0738569779880000/19731 | name | ef:agent/bootstrap_labels | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v1 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v2 |
| ef:activity/change/20260820T0738569779880000/19732 | synonyms | ef:agent/bootstrap_labels | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v2 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v3 |
| ef:activity/change/20260820T0738569779880000/193008 | context | ef:agent/default_context_mapping | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v3 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v4 |
| ef:activity/change/20260820T0738569779880000/193009 | context_iri | ef:agent/default_context_mapping | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v4 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v5 |
| ef:activity/change/20260820T0738569779880000/219759 | unit_iri | ef:agent/unit_normalization | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v5 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v6 |
| ef:activity/change/20260820T0738569779880000/245499 | properties | ef:agent/enrich_references | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v6 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v7 |
| ef:activity/change/20260820T0738569779880000/245500 | skos_definition | ef:agent/enrich_references | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v7 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v8 |
| ef:activity/change/20260820T0738569779880000/245501 | references | ef:agent/enrich_references | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v8 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v9 |
| ef:activity/change/20260820T0738569779880000/253604 | properties | ef:agent/rdkit_pre_consensus | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v9 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v10 |
| ef:activity/change/20260820T0738569779880000/256955 | altLabel | ef:agent/chebi_altlabels | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v10 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v11 |
| ef:activity/change/20260820T0738569779880000/259361 | prefLabel | ef:agent/consensus_match | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v11 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v12 |
| ef:activity/change/20260820T0738569779880000/259362 | altLabel | ef:agent/consensus_match | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v12 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v13 |
| ef:activity/change/20260820T0738569779880000/259363 | altLabel | ef:agent/consensus_match | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v13 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v14 |
| ef:activity/change/20260820T0738569779880000/259364 | cas_match_labels | ef:agent/consensus_match | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v14 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v15 |
| ef:activity/change/20260820T0738569779880000/278834 | properties | ef:agent/opsin_iupac | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v15 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v16 |
| ef:activity/change/20260820T0738569779880000/285628 | properties | ef:agent/rdkit_post_consensus | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v16 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v17 |
| ef:activity/change/20260820T0738569779880000/291227 | altLabel | ef:agent/strip_catalogue_altlabels | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v17 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v18 |
| ef:activity/change/20260820T0738569779880000/377556 | concept_associations | ef:agent/carry_associations_onto_flows | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v18 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v19 |
| ef:activity/change/20260820T0738569779880000/393208 | properties | ef:agent/normalise_property_values | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v19 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v20 |
| ef:activity/change/20260820T0738569779880000/402048 | types | ef:agent/link_flows_to_their_substance | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v20 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v21 |
| ef:activity/change/20260820T0738569779880000/402049 | properties | ef:agent/link_flows_to_their_substance | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v21 | ef:flow/efa43def-7f88-4a85-b8e6-b5dba0325ecb/v22 |