Losartan
Everything that changed this flow. Back to the flow
f18514c3-6c85-40f7-9231-5bd36ab73f0f
By field
13 fields| Field | Changes | Written by | Latest note |
|---|---|---|---|
| properties | 5 | enrich_references, normalise_property_values, opsin_iupac, rdkit_post_consensus, rdkit_pre_consensus | typed the way the ontology types it |
| altLabel | 4 | chebi_altlabels, consensus_match, strip_catalogue_altlabels | Removed 1 catalogue altLabel value(s): 'DUP 89' (grade code) |
| prefLabel | 2 | bootstrap_labels, consensus_match | cas=114798-26-4; cc_chebi_agreed_name='Losartan'; object_uuid=fo-71d33d9cf32dbbc6 |
| cas_match_labels | 1 | consensus_match | group_key=[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol||dimension=Environmental > media=Water > water_body=Long-term; group_sources=['chebi', 'pubchem']; cas_sources={'114798-26-4': ['chebi', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-71d33d9cf32dbbc6: {'114798-26-4': 'exactMatch'} |
| concept_associations | 1 | carry_associations_onto_flows | associations resolved on the elementary layer |
| context | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| context_iri | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| name | 1 | bootstrap_labels | Purged legacy name field to enforce prefLabel usage |
| references | 1 | enrich_references | Added references with provenance; cas_numbers=['114798-26-4']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_6541']; candidate_pubchem_cids=[3961, 24848371, 29934697]; selected_pubchem_cids=[3961]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| skos_definition | 1 | enrich_references | Merged ChEBI/PubChem definitions into skos:definition |
| synonyms | 1 | bootstrap_labels | Removed legacy synonyms field in favor of structured labels |
| types | 1 | link_flows_to_their_substance | the substance's answer, copied onto its flow |
| unit_iri | 1 | unit_normalization | Unit IRI set from normalization of 'kg' |
Where several steps wrote one field, the last one won — and the log below shows the sequence.
Changes
21| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 20,683 | bootstrap_labels | prefLabel | — | [{"@value":"[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol","@lan… | Bootstrapped prefLabel from legacy name field |
| 20,684 | bootstrap_labels | name | [2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol | — | Purged legacy name field to enforce prefLabel usage |
| 20,685 | bootstrap_labels | synonyms | ["organic","1h-imidazole-5-methanol,2-butyl-4-chloro-1-[[2'","-(2h-tetrazol-5-yl)[1,1'","-biphenyl]-4-yl]methyl… | [] | Removed legacy synonyms field in favor of structured labels |
| 194,040 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Air","strata":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 194,041 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-air-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to air > Emissions to air, unspecified (long-term) |
| 220,022 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 246,244 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 246,245 | enrich_references | skos_definition | — | [{"@value":"A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisu… | Merged ChEBI/PubChem definitions into skos:definition |
| 246,246 | enrich_references | references | [] | [{"@id":"drugcentral:1610","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":"… | Added references with provenance; cas_numbers=['114798-26-4']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_6541']; candidate_pubchem_cids=[3961, 24848371, 29934697]; selected_pubchem_cids=[3961]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 253,817 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | rdkit_pre_consensus from 'CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4)CO)Cl'; added: monoisotopic_mass |
| 257,026 | chebi_altlabels | altLabel | [] | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | Added 5 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 263,427 | consensus_match | prefLabel | [{"@value":"[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol","@lan… | [{"@value":"Losartan","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttributedTo":"consen… | cas=114798-26-4; cc_chebi_agreed_name='Losartan'; object_uuid=fo-71d33d9cf32dbbc6 |
| 263,428 | consensus_match | altLabel | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | cas=114798-26-4; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-71d33d9cf32dbbc6 |
| 263,429 | consensus_match | altLabel | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | group_key=[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol||dimension=Environmental > media=Water > water_body=Long-term; cas=114798-26-4; added Common Chemistry CAS names as altLabel: 1-[1-[[2′-(2<em>H</em>-Tetrazol-5-yl)biphenyl-4-yl]methyl]-2-butyl-4-chloro-1<em>H</em>-imidazol-5-yl]methanol, 1<em>H</em>-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2′-(1<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, 1<em>H</em>-Imidazole-5-methanol, 2-butyl-4-chloro-1-[[2′-(2<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-, 2-Butyl-4-chloro-1-[[2′-(1<em>H</em>-tetrazol-5-yl)-1,1′-biphenyl-4-yl]methyl]-1<em>H</em>-imidazole-5-methanol, 2-Butyl-4-chloro-1-[[2′-(2<em>H</em>-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-1<em>H</em>-imidazole-5-methanol, Allisartan, Angizaar, DUP 89, Lortaan, Lozap, MeSH ID: D019808, Xartan, [2-Butyl-4-chloro-1-([4-[2-(1<em>H</em>-1,2,3,4-tetrazol-5-yl)phenyl]phenyl]methyl)-1<em>H</em>-imidazol-5-yl]methanol, [2-Butyl-5-chloro-3-[2′-(2<em>H</em>-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3<em>H</em>-imidazol-4-yl]-methanol, [2-Butyl-5-chloro-3-[[4-[2-(2<em>H</em>-tetrazol-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol; object_uuid=fo-71d33d9cf32dbbc6 |
| 263,430 | consensus_match | cas_match_labels | — | {"114798-26-4":"exactMatch"} | group_key=[2-butyl-4-chloro-1-({4-[2-(2h-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1h-imidazol-5-yl]methanol||dimension=Environmental > media=Water > water_body=Long-term; group_sources=['chebi', 'pubchem']; cas_sources={'114798-26-4': ['chebi', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-71d33d9cf32dbbc6: {'114798-26-4': 'exactMatch'} |
| 279,019 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol' |
| 285,846 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | rdkit_post_consensus from 'CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 291,362 | strip_catalogue_altlabels | altLabel | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | [{"@value":"(2-butyl-4-chloro-1-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-1H-imidazol-5-yl)methanol","@langua… | Removed 1 catalogue altLabel value(s): 'DUP 89' (grade code) |
| 378,052 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/f18514c3-6c85-… | associations resolved on the elementary layer |
| 393,401 | normalise_property_values | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C22H23ClN6… | typed the way the ontology types it |
| 402,342 | link_flows_to_their_substance | types | — | ["https://w3id.org/chemrof/NeutralMolecule"] | the substance's answer, copied onto its flow |
PROV-O trail
21 activitiesOne activity per change: which version of the flow it consumed, and which it produced. The values are on the change with the same number — stored once, not twice.
| Activity | Field | Agent | Used | Generated |
|---|---|---|---|---|
| ef:activity/change/20260822T0600486828500000/20683 | prefLabel | ef:agent/bootstrap_labels | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v0 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v1 |
| ef:activity/change/20260822T0600486828500000/20684 | name | ef:agent/bootstrap_labels | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v1 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v2 |
| ef:activity/change/20260822T0600486828500000/20685 | synonyms | ef:agent/bootstrap_labels | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v2 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v3 |
| ef:activity/change/20260822T0600486828500000/194040 | context | ef:agent/default_context_mapping | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v3 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v4 |
| ef:activity/change/20260822T0600486828500000/194041 | context_iri | ef:agent/default_context_mapping | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v4 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v5 |
| ef:activity/change/20260822T0600486828500000/220022 | unit_iri | ef:agent/unit_normalization | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v5 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v6 |
| ef:activity/change/20260822T0600486828500000/246244 | properties | ef:agent/enrich_references | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v6 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v7 |
| ef:activity/change/20260822T0600486828500000/246245 | skos_definition | ef:agent/enrich_references | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v7 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v8 |
| ef:activity/change/20260822T0600486828500000/246246 | references | ef:agent/enrich_references | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v8 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v9 |
| ef:activity/change/20260822T0600486828500000/253817 | properties | ef:agent/rdkit_pre_consensus | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v9 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v10 |
| ef:activity/change/20260822T0600486828500000/257026 | altLabel | ef:agent/chebi_altlabels | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v10 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v11 |
| ef:activity/change/20260822T0600486828500000/263427 | prefLabel | ef:agent/consensus_match | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v11 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v12 |
| ef:activity/change/20260822T0600486828500000/263428 | altLabel | ef:agent/consensus_match | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v12 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v13 |
| ef:activity/change/20260822T0600486828500000/263429 | altLabel | ef:agent/consensus_match | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v13 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v14 |
| ef:activity/change/20260822T0600486828500000/263430 | cas_match_labels | ef:agent/consensus_match | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v14 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v15 |
| ef:activity/change/20260822T0600486828500000/279019 | properties | ef:agent/opsin_iupac | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v15 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v16 |
| ef:activity/change/20260822T0600486828500000/285846 | properties | ef:agent/rdkit_post_consensus | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v16 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v17 |
| ef:activity/change/20260822T0600486828500000/291362 | altLabel | ef:agent/strip_catalogue_altlabels | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v17 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v18 |
| ef:activity/change/20260822T0600486828500000/378052 | concept_associations | ef:agent/carry_associations_onto_flows | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v18 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v19 |
| ef:activity/change/20260822T0600486828500000/393401 | properties | ef:agent/normalise_property_values | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v19 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v20 |
| ef:activity/change/20260822T0600486828500000/402342 | types | ef:agent/link_flows_to_their_substance | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v20 | ef:flow/f18514c3-6c85-40f7-9231-5bd36ab73f0f/v21 |