Melphalan
Everything that changed this flow. Back to the flow
fe0acd60-3ddc-11dd-a02b-0050c2490048
By field
13 fields| Field | Changes | Written by | Latest note |
|---|---|---|---|
| properties | 6 | enrich_references, link_flows_to_their_substance, normalise_property_values, opsin_iupac, rdkit_post_consensus, rdkit_pre_consensus | the substance's answer, copied onto its flow |
| altLabel | 4 | chebi_altlabels, consensus_match, strip_catalogue_altlabels | Removed 3 catalogue altLabel value(s): 'CB 3025' (grade code), 'NSC 241286' (registry code), 'NSC 8806' (registry code) |
| prefLabel | 3 | bootstrap_labels, consensus_match, normalize_name_case | cas=148-82-3; cc_chebi_agreed_name='Melphalan'; object_uuid=fo-2379f5b4f316c79b |
| cas_match_labels | 1 | consensus_match | group_key=phenylalaninemustard||dimension=Environmental > media=Air > strata=Aircraft cruise height; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'148-82-3': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-2379f5b4f316c79b: {'148-82-3': 'exactMatch'} |
| concept_associations | 1 | carry_associations_onto_flows | associations resolved on the elementary layer |
| context | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| context_iri | 1 | default_context_mapping | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| name | 1 | bootstrap_labels | Purged legacy name field to enforce prefLabel usage |
| references | 1 | enrich_references | Added references with provenance; cas_numbers=['148-82-3']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_28876']; candidate_pubchem_cids=[4053, 460612, 9927978, 66780577]; selected_pubchem_cids=[460612]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| skos_definition | 1 | enrich_references | Merged ChEBI/PubChem definitions into skos:definition |
| synonyms | 1 | bootstrap_labels | Removed legacy synonyms field in favor of structured labels |
| types | 1 | link_flows_to_their_substance | the substance's answer, copied onto its flow |
| unit_iri | 1 | unit_normalization | Unit IRI set from normalization of 'kg' |
Where several steps wrote one field, the last one won — and the log below shows the sequence.
Changes
23| # | Step | Field | From | To | Why |
|---|---|---|---|---|---|
| 3,479 | bootstrap_labels | prefLabel | — | [{"@value":"phenylalanine mustard","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttribu… | Bootstrapped prefLabel from legacy name field |
| 3,480 | bootstrap_labels | name | phenylalanine mustard | — | Purged legacy name field to enforce prefLabel usage |
| 3,481 | bootstrap_labels | synonyms | ["(+)-3-(p-(Bis(2-chloroethyl)amino)phenyl)alanine","(+)-3-[p-[Bis(2-chloroethyl)amino]phenyl]alanine","(p-Di(2-chloroe… | [] | Removed legacy synonyms field in favor of structured labels |
| 203,330 | default_context_mapping | context | — | {"dimension":"Environmental","media":"Water","water_body":"Long-term"} | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 203,331 | default_context_mapping | context_iri | — | https://vocab.brightway.one/flow-contexts/envi-wate-lote | Mapped from context mapping for source=EF 3.1, source context Emissions > Emissions to water > Emissions to water, unspecified (long-term) |
| 214,500 | unit_normalization | unit_iri | — | https://vocab.brightway.one/units/unit/KiloGM | Unit IRI set from normalization of 'kg' |
| 221,896 | normalize_name_case | prefLabel | [{"@value":"phenylalanine mustard","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttribu… | [{"@value":"Phenylalanine Mustard","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttribu… | Title-cased words without internal capitals (preserved words with uppercase letters beyond the first character) |
| 230,534 | enrich_references | properties | {} | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | Added ChEBI/PubChem properties (chebi_ids=1, pubchem_cids=1) |
| 230,535 | enrich_references | skos_definition | — | [{"@value":"A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-positi… | Merged ChEBI/PubChem definitions into skos:definition |
| 230,536 | enrich_references | references | [] | [{"@id":"drugcentral:1678","provenance":{"prov:wasGeneratedBy":"enrich_references.chebi_xrefs","prov:wasAttributedTo":"… | Added references with provenance; cas_numbers=['148-82-3']; matched_chebi_ids=['http://purl.obolibrary.org/obo/CHEBI_28876']; candidate_pubchem_cids=[4053, 460612, 9927978, 66780577]; selected_pubchem_cids=[460612]; formula_similarity_expected=[]; pubchem_selection_rule=curated_cas_then_formula_similarity_then_prefer_chebi_aligned_when_unambiguous_else_keep_all_cas_matches; single_cas_commonchem_link=yes |
| 249,289 | rdkit_pre_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | rdkit_pre_consensus from 'C1=CC(=CC=C1CC(C(=O)O)N)N(CCCl)CCCl'; added: inchi2d_string, monoisotopic_mass |
| 254,804 | chebi_altlabels | altLabel | [] | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | Added 17 ChEBI synonym(s) as altLabel from 1 linked ChEBI record(s) |
| 270,639 | consensus_match | prefLabel | [{"@value":"Phenylalanine Mustard","@language":"en","source":{"prov:wasGeneratedBy":"bootstrap_labels","prov:wasAttribu… | [{"@value":"Melphalan","@language":"en","source":{"prov:wasGeneratedBy":"consensus_match","prov:wasAttributedTo":"conse… | cas=148-82-3; cc_chebi_agreed_name='Melphalan'; object_uuid=fo-2379f5b4f316c79b |
| 270,640 | consensus_match | altLabel | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | cas=148-82-3; added original name as altLabel after CC/ChEBI rename; object_uuid=fo-2379f5b4f316c79b |
| 270,641 | consensus_match | altLabel | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | group_key=phenylalaninemustard||dimension=Environmental > media=Air > strata=Aircraft cruise height; cas=148-82-3; added Common Chemistry CAS names as altLabel: 3025CB, 67: PN: WO2010011890 PAGE: 37 claimed protein, <span class="text-smallcaps">L</span>-Phenylalanine mustard hydrochloride, <span class="text-smallcaps">L</span>-Phenylalanine, 4-[bis(2-chloroethyl)amino]-, <span class="text-smallcaps">L</span>-Sarcolysin, <span class="text-smallcaps">L</span>-Sarkolysin, Alanine nitrogen mustard, Alanine, 3-[<em>p</em>-[bis(2-chloroethyl)amino]phenyl]-, <span class="text-smallcaps">L</span>-, Alkeran, CB 3025, Levofalan, Levofolan, Levopholan, MeSH ID: D008558, Melfalan, NSC 241286, NSC 8806, Sarcoclorin; object_uuid=fo-2379f5b4f316c79b |
| 270,642 | consensus_match | cas_match_labels | — | {"148-82-3":"exactMatch"} | group_key=phenylalaninemustard||dimension=Environmental > media=Air > strata=Aircraft cruise height; group_sources=['chebi', 'ec_inventory', 'pubchem']; cas_sources={'148-82-3': ['chebi', 'ec_inventory', 'pubchem']}; assigned CAS labels from group consensus; object_uuid=fo-2379f5b4f316c79b: {'148-82-3': 'exactMatch'} |
| 274,411 | opsin_iupac | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | opsin_iupac: set authoritative IUPAC name, SMILES, InChI from '3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine' |
| 280,847 | rdkit_post_consensus | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | rdkit_post_consensus from 'N[C@@H](Cc1ccc(N(CCCl)CCCl)cc1)C(=O)O'; confirmed: smiles_string, inchi2d_string, inchi2d_key_string, molecular_formula, molecular_mass, monoisotopic_mass |
| 287,963 | strip_catalogue_altlabels | altLabel | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | [{"@value":"3-(p-(Bis(2-chloroethyl)amino)phenyl)-L-alanine","@language":"en","source":{"prov:wasGeneratedBy":"chebi_al… | Removed 3 catalogue altLabel value(s): 'CB 3025' (grade code), 'NSC 241286' (registry code), 'NSC 8806' (registry code) |
| 382,699 | carry_associations_onto_flows | concept_associations | [] | [{"@type":"xkos:ConceptAssociation","xkos:sourceConcept":{"@id":"https://vocab.brightway.one/ef/3.1/flow/fe0acd60-3ddc-… | associations resolved on the elementary layer |
| 388,705 | normalise_property_values | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | typed the way the ontology types it |
| 395,547 | link_flows_to_their_substance | types | — | ["https://w3id.org/chemrof/NeutralMolecule"] | the substance's answer, copied onto its flow |
| 395,548 | link_flows_to_their_substance | properties | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | {"https://w3id.org/chemrof/molecular_formula":{"@id":"https://w3id.org/chemrof/molecular_formula","@value":["C13H18Cl2N… | the substance's answer, copied onto its flow |
PROV-O trail
23 activitiesOne activity per change: which version of the flow it consumed, and which it produced. The values are on the change with the same number — stored once, not twice.
| Activity | Field | Agent | Used | Generated |
|---|---|---|---|---|
| ef:activity/change/20260822T0600486828500000/3479 | prefLabel | ef:agent/bootstrap_labels | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v0 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v1 |
| ef:activity/change/20260822T0600486828500000/3480 | name | ef:agent/bootstrap_labels | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v1 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v2 |
| ef:activity/change/20260822T0600486828500000/3481 | synonyms | ef:agent/bootstrap_labels | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v2 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v3 |
| ef:activity/change/20260822T0600486828500000/203330 | context | ef:agent/default_context_mapping | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v3 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v4 |
| ef:activity/change/20260822T0600486828500000/203331 | context_iri | ef:agent/default_context_mapping | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v4 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v5 |
| ef:activity/change/20260822T0600486828500000/214500 | unit_iri | ef:agent/unit_normalization | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v5 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v6 |
| ef:activity/change/20260822T0600486828500000/221896 | prefLabel | ef:agent/normalize_name_case | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v6 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v7 |
| ef:activity/change/20260822T0600486828500000/230534 | properties | ef:agent/enrich_references | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v7 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v8 |
| ef:activity/change/20260822T0600486828500000/230535 | skos_definition | ef:agent/enrich_references | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v8 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v9 |
| ef:activity/change/20260822T0600486828500000/230536 | references | ef:agent/enrich_references | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v9 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v10 |
| ef:activity/change/20260822T0600486828500000/249289 | properties | ef:agent/rdkit_pre_consensus | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v10 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v11 |
| ef:activity/change/20260822T0600486828500000/254804 | altLabel | ef:agent/chebi_altlabels | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v11 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v12 |
| ef:activity/change/20260822T0600486828500000/270639 | prefLabel | ef:agent/consensus_match | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v12 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v13 |
| ef:activity/change/20260822T0600486828500000/270640 | altLabel | ef:agent/consensus_match | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v13 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v14 |
| ef:activity/change/20260822T0600486828500000/270641 | altLabel | ef:agent/consensus_match | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v14 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v15 |
| ef:activity/change/20260822T0600486828500000/270642 | cas_match_labels | ef:agent/consensus_match | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v15 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v16 |
| ef:activity/change/20260822T0600486828500000/274411 | properties | ef:agent/opsin_iupac | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v16 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v17 |
| ef:activity/change/20260822T0600486828500000/280847 | properties | ef:agent/rdkit_post_consensus | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v17 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v18 |
| ef:activity/change/20260822T0600486828500000/287963 | altLabel | ef:agent/strip_catalogue_altlabels | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v18 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v19 |
| ef:activity/change/20260822T0600486828500000/382699 | concept_associations | ef:agent/carry_associations_onto_flows | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v19 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v20 |
| ef:activity/change/20260822T0600486828500000/388705 | properties | ef:agent/normalise_property_values | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v20 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v21 |
| ef:activity/change/20260822T0600486828500000/395547 | types | ef:agent/link_flows_to_their_substance | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v21 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v22 |
| ef:activity/change/20260822T0600486828500000/395548 | properties | ef:agent/link_flows_to_their_substance | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v22 | ef:flow/fe0acd60-3ddc-11dd-a02b-0050c2490048/v23 |